IL12A

Across TCGA patient cohorts, IL12A RNA expression is significantly associated with the protein abundance of many other proteins, with 8,861 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IL12A-associated proteins across cancer lineages are LGALS9, GBP4, and PRAG1. Each is linked with IL12A in more than 3 cancer types. Because this analysis shows association rather than direction, both IL12A-to-partner and partner-to-IL12A results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL12A versus LGALS9 in HNSC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL12A→partner) and Y-score (partner→IL12A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	LGALS9 →	+0.697	+0.694	<.001	.002	3	4
BRCA	GBP4 →	+0.794	+0.858	<.001	<.001	3	4
OV	PRAG1 →	-0.358	-1.557	.004	<.001	3	4
BRCA	QKI →	+0.280	+0.704	.003	.008	3	3
HNSC	WIPF1 →	+0.304	+0.525	.002	.003	3	3
PDAC	SH3BGRL3 →	-0.550	-0.237	<.001	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,861 associations by consensus.

IL12A vs LGALS9 — HNSC

Explore this scatter interactively →