IL11

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IL11 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,318 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL11-associated proteins across cancer lineages are C1R, FN1, and SULF1. Each is linked with IL11 in more than 7 cancer types. Because this analysis shows association rather than direction, both IL11-to-partner and partner-to-IL11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL11 versus C1R in OV, with a Pearson correlation of 0.49.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL11→partner) and Y-score (partner→IL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVC1R →+0.792+1.082<.001<.00138
OVFN1 →+0.858+0.747<.001<.00138
GBMSULF1 →+0.785+0.651<.001.00437
OVTIMP2 →+0.748+1.037<.001<.00137
GBMMYH9 →+0.582+1.170<.001<.00137
UCECMYH9_S1340 →+0.722+0.951.005.00637
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,318 associations by consensus.

IL11 vs C1R — OV

Per-sample scatter of IL11 vs C1R in OV (Pearson r = 0.49).

Explore this scatter interactively →

Exploration