IL10RB

Across TCGA patient cohorts, IL10RB RNA expression is significantly associated with the protein abundance of many other proteins, with 8,157 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IL10RB-associated proteins across cancer lineages are ARRB2, FAM110C_S202, and KRT17_S32. Each is linked with IL10RB in more than 3 cancer types. Because this analysis shows association rather than direction, both IL10RB-to-partner and partner-to-IL10RB results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL10RB versus ARRB2 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL10RB→partner) and Y-score (partner→IL10RB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	ARRB2 →	+0.299	+0.213	<.001	<.001	3	4
UCEC	FAM110C_S202 →	-0.927	-0.375	.005	.003	3	3
LSCC	KRT17_S32 →	-1.283	-0.195	.006	.009	3	3
PDAC	LSP1_S177 →	+0.622	+0.220	.001	.002	3	3
LSCC	STXBP2 →	+0.288	+0.271	<.001	<.001	3	3
LSCC	BIN2_S458 →	+0.807	+0.261	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,157 associations by consensus.

IL10RB vs ARRB2 — LSCC

Explore this scatter interactively →