IL10RA

Across TCGA patient cohorts, IL10RA RNA expression is significantly associated with the protein abundance of many other proteins, with 23,066 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IL10RA-associated proteins across cancer lineages are PLEKHO2_T311, ARHGEF6_S225, and PTPN6. Each is linked with IL10RA in more than 9 cancer types. Because this analysis shows association rather than direction, both IL10RA-to-partner and partner-to-IL10RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL10RA versus PLEKHO2_T311 in LSCC, with a Pearson correlation of 0.78.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IL10RA→partner) and Y-score (partner→IL10RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLEKHO2_T311 →	+0.564	+0.929	<.001	<.001	3	10
LSCC	ARHGEF6_S225 →	+0.857	+1.068	<.001	<.001	3	10
GBM	PTPN6 →	+0.788	+1.421	<.001	<.001	3	10
COAD	PTPN7 →	+0.618	+0.919	<.001	<.001	3	10
GBM	PTPRC →	+0.907	+1.475	<.001	<.001	3	10
OV	RAC2 →	+0.850	+1.040	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 23,066 associations by consensus.

IL10RA vs PLEKHO2_T311 — LSCC

Explore this scatter interactively →