IL10RA

Across TCGA patient cohorts, IL10RA protein abundance is significantly associated with the RNA expression of many other genes, with 685 significant associations in total. LUAD shows the largest number of these associations.

The most reproducible IL10RA-associated genes across cancer lineages are TOP3B, PABPC1L, and ABCD1. Each is linked with IL10RA in more than 1 cancer types. Because this analysis shows association rather than direction, both IL10RA-to-partner and partner-to-IL10RA results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IL10RA versus TOP3B in LUAD, with a Pearson correlation of -0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IL10RA→partner) and Y-score (partner→IL10RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	TOP3B →	-0.281	-1.089	.001	.004	3	1
LUAD	PABPC1L →	-1.330	-0.902	.001	.001	3	1
LUAD	ABCD1 →	-0.843	-0.783	.001	.004	3	1
LUAD	MGRN1 →	-0.773	-1.098	.009	.003	3	1
LUAD	USB1 →	-0.819	-0.885	<.001	<.001	3	1
LUAD	NAGPA →	-0.592	-0.787	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 685 associations by consensus.

IL10RA vs TOP3B — LUAD

Explore this scatter interactively →