IL10RA

Across TCGA cell cohorts, IL10RA RNA expression is significantly associated with the go_rna of many other GO terms, with 2,389 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IL10RA-associated GO terms across cancer lineages are Cytoplasmic translation, Negative regulation of syncytium formation by plasma membrane fusion, and Proton motive force-driven ATP synthesis. Each is linked with IL10RA in more than 8 cancer types. Because this analysis shows association rather than direction, both IL10RA-to-partner and partner-to-IL10RA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytoplasmic translation grouped by IL10RA-low versus IL10RA-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IL10RA→partner) and Y-score (partner→IL10RA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Cytoplasmic translation →	+0.076	+0.347	<.001	.001	3	8
BREAST	Negative regulation of syncytium formation by plasma membrane fusion →	+0.103	+0.164	<.001	<.001	3	8
OVARY	Proton motive force-driven ATP synthesis →	+0.120	+0.242	<.001	<.001	3	8
KIDNEY	Cellular response to nutrient levels →	+0.038	+0.296	<.001	.001	3	8
CNS	Regulation of macroautophagy →	+0.032	+0.126	<.001	.006	3	8
OVARY	Lysosomal lumen acidification →	+0.101	+0.233	<.001	.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,389 associations by consensus.

Cytoplasmic translation by IL10RA expression — PANCREAS

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