IKZF4

Across TCGA cell cohorts, IKZF4 RNA expression is significantly associated with the RNA expression of many other genes, with 11,163 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IKZF4-associated genes across cancer lineages are DNAJC14, UBN2, and KMT2D. Each is linked with IKZF4 in more than 14 cancer types. Because this analysis shows association rather than direction, both IKZF4-to-partner and partner-to-IKZF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IKZF4 versus DNAJC14 in UPPER_AERODIGESTIVE_TRACT, with a Pearson correlation of 0.57.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IKZF4→partner) and Y-score (partner→IKZF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	DNAJC14 →	+1.297	+0.918	<.001	<.001	3	15
LUNG_SCLC	UBN2 →	+0.929	+0.647	<.001	<.001	3	15
PANCREAS	KMT2D →	+1.454	+0.749	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	SETD5 →	+1.905	+0.871	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	TSC1 →	+1.293	+0.841	<.001	<.001	3	14
URINARY_TRACT	NR2C2 →	+1.213	+0.684	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,163 associations by consensus.

IKZF4 vs DNAJC14 — UPPER_AERODIGESTIVE_TRACT

Explore this scatter interactively →