IKZF3

Across TCGA patient cohorts, IKZF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 19,262 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IKZF3-associated proteins across cancer lineages are APOL3, ARHGAP15, and ARHGAP15_S64. Each is linked with IKZF3 in more than 9 cancer types. Because this analysis shows association rather than direction, both IKZF3-to-partner and partner-to-IKZF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IKZF3 versus APOL3 in HNSC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IKZF3→partner) and Y-score (partner→IKZF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	APOL3 →	+0.847	+1.244	<.001	<.001	3	10
GBM	ARHGAP15 →	+0.730	+0.807	<.001	<.001	3	10
LSCC	ARHGAP15_S64 →	+0.986	+1.114	<.001	<.001	3	10
OV	ARHGAP25 →	+0.801	+1.181	.002	<.001	3	10
OV	ARHGAP30 →	+1.001	+1.583	<.001	<.001	3	10
GBM	ACAP1 →	+0.730	+0.957	.008	.002	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 19,262 associations by consensus.

IKZF3 vs APOL3 — HNSC

Explore this scatter interactively →