IKBKE

Across TCGA patient cohorts, IKBKE protein abundance is significantly associated with the RNA expression of many other genes, with 15,221 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IKBKE-associated genes across cancer lineages are CSF2RB, MEFV, and IL21R. Each is linked with IKBKE in more than 6 cancer types. Because this analysis shows association rather than direction, both IKBKE-to-partner and partner-to-IKBKE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IKBKE versus CSF2RB in UCEC, with a Pearson correlation of 0.50.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IKBKE→partner) and Y-score (partner→IKBKE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CSF2RB →	+1.238	+0.490	<.001	<.001	3	7
HNSC	MEFV →	+0.946	+0.468	<.001	<.001	3	6
UCEC	IL21R →	+1.057	+0.361	.002	.004	3	6
GBM	AQP9 →	+1.454	+0.768	<.001	<.001	3	6
GBM	JAK3 →	+0.845	+0.533	<.001	<.001	3	6
UCEC	VNN2 →	+1.285	+0.431	.003	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,221 associations by consensus.

IKBKE vs CSF2RB — UCEC

Explore this scatter interactively →