IKBKE

Across TCGA cell cohorts, IKBKE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,591 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible IKBKE-associated GO terms across cancer lineages are Positive regulation of lipid storage, Regulation of cytokine-mediated signaling pathway, and Response to interleukin-17. Each is linked with IKBKE in more than 13 cancer types. Because this analysis shows association rather than direction, both IKBKE-to-partner and partner-to-IKBKE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of lipid storage grouped by IKBKE-low versus IKBKE-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IKBKE→partner) and Y-score (partner→IKBKE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Positive regulation of lipid storage →	+0.164	+1.255	.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of cytokine-mediated signaling pathway →	+0.081	+1.112	.001	<.001	3	14
OESOPHAGUS	Response to interleukin-17 →	+0.109	+1.422	<.001	.001	3	14
OESOPHAGUS	Cellular response to interleukin-17 →	+0.109	+1.422	<.001	.001	3	14
LUNG_SCLC	Antigen processing and presentation of endogenous peptide antigen →	+0.271	+1.780	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Positive regulation of cytokine-mediated signaling pathway →	+0.136	+1.186	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,591 associations by consensus.

Positive regulation of lipid storage by IKBKE expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →