IKBKB

Across TCGA cell cohorts, IKBKB RNA expression is significantly associated with the go_rna of many other GO terms, with 3,534 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible IKBKB-associated GO terms across cancer lineages are Cytosolic transport, Regulation of telomere capping, and snoRNA guided rRNA pseudouridine synthesis. Each is linked with IKBKB in more than 13 cancer types. Because this analysis shows association rather than direction, both IKBKB-to-partner and partner-to-IKBKB results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytosolic transport grouped by IKBKB-low versus IKBKB-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IKBKB→partner) and Y-score (partner→IKBKB) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Cytosolic transport →	+0.070	+1.111	<.001	<.001	3	14
UPPER_AERODIGESTIVE_TRACT	Regulation of telomere capping →	+0.099	+1.076	<.001	<.001	3	14
SKIN	snoRNA guided rRNA pseudouridine synthesis →	-0.106	-0.729	<.001	<.001	3	14
BONE	Pre-mRNA catabolic process →	+0.243	+0.961	<.001	<.001	3	13
BONE	Regulation of pattern recognition receptor signaling pathway →	+0.069	+0.948	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Endocytic recycling →	+0.059	+1.060	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,534 associations by consensus.

Cytosolic transport by IKBKB expression — SKIN

Explore this box plot interactively →