IHO1

Across TCGA patient cohorts, IHO1 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,509 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IHO1-associated proteins across cancer lineages are PDGFRB, RCN3, and AEBP1. Each is linked with IHO1 in more than 7 cancer types. Because this analysis shows association rather than direction, both IHO1-to-partner and partner-to-IHO1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IHO1 versus PDGFRB in BRCA, with a Pearson correlation of 0.66.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IHO1→partner) and Y-score (partner→IHO1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	PDGFRB →	+0.519	+0.525	<.001	<.001	3	8
CCRCC	RCN3 →	+0.635	+0.575	<.001	<.001	3	8
CCRCC	AEBP1 →	+0.878	+0.530	<.001	<.001	3	8
BRCA	COL1A1 →	+0.964	+0.552	<.001	<.001	3	8
BRCA	COL3A1 →	+0.831	+0.521	<.001	<.001	3	8
BRCA	COL5A2 →	+0.805	+0.464	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,509 associations by consensus.

IHO1 vs PDGFRB — BRCA

Explore this scatter interactively →