IGSF9

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGSF9 protein abundance is significantly associated with the RNA expression of many other genes, with 7,940 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGSF9-associated genes across cancer lineages are KLHL12, TNNT2, and SOX4. Each is linked with IGSF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGSF9-to-partner and partner-to-IGSF9 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF9 versus KLHL12 in LSCC, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF9→partner) and Y-score (partner→IGSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LSCCKLHL12 →+0.495+0.948.004<.00132
OVTNNT2 →+0.610+0.646<.001<.00132
LUADSOX4 →+0.866+0.876.006.00632
LUADSTK35 →+0.728+1.486<.001.00432
LSCCCOG2 →+0.548+0.878<.001.00132
LSCCEPC2 →+0.470+0.904.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 7,940 associations by consensus.

IGSF9 vs KLHL12 — LSCC

Per-sample scatter of IGSF9 vs KLHL12 in LSCC (Pearson r = 0.40).

Explore this scatter interactively →

Exploration