IGSF9

Across TCGA cell cohorts, IGSF9 mutation is significantly associated with the RNA expression of many other genes, with 437 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IGSF9-associated genes across cancer lineages are RBMY1J, CST9, and MBD3L3. Each is linked with IGSF9 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGSF9-to-partner and partner-to-IGSF9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RBMY1J grouped by IGSF9-low versus IGSF9-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF9→partner) and Y-score (partner→IGSF9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	RBMY1J →	+0.052	+4.930	<.001	.008	3	2
OVARY	CST9 →	+0.005	+4.807	<.001	.003	3	2
OESOPHAGUS	MBD3L3 →	+0.020	+4.906	<.001	.006	3	1
OESOPHAGUS	RXFP3 →	+0.006	+4.906	<.001	.006	3	1
OESOPHAGUS	MBD3L4 →	+0.020	+4.906	<.001	.006	3	1
BLOOD_Myeloma	OR1E2 →	+0.210	+4.807	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 437 associations by consensus.

RBMY1J by IGSF9 expression — SOFT_TISSUE

Explore this box plot interactively →