IGSF3

Across TCGA patient cohorts, IGSF3 RNA expression is significantly associated with the protein abundance of many other proteins, with 14,202 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGSF3-associated proteins across cancer lineages are SNX4, GTF2I, and TBXAS1. Each is linked with IGSF3 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGSF3-to-partner and partner-to-IGSF3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF3 versus SNX4 in BRCA, with a Pearson correlation of 0.37.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF3→partner) and Y-score (partner→IGSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	SNX4 →	+0.255	+0.780	<.001	.001	3	5
GBM	GTF2I →	+0.398	+1.014	<.001	<.001	3	5
LSCC	TBXAS1 →	-0.495	-1.017	<.001	<.001	3	4
GBM	THEMIS2 →	-0.400	-0.910	<.001	<.001	3	4
GBM	TRIM33 →	+0.244	+1.123	<.001	<.001	3	4
GBM	PTPRC →	-0.574	-0.954	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,202 associations by consensus.

IGSF3 vs SNX4 — BRCA

Explore this scatter interactively →