IGSF3

Across TCGA cell cohorts, IGSF3 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,532 significant associations in total. BONE shows the largest number of these associations.

The most reproducible IGSF3-associated GO terms across cancer lineages are Lacrimal gland development, Aerobic respiration, and Cytoplasmic translation. Each is linked with IGSF3 in more than 19 cancer types. Because this analysis shows association rather than direction, both IGSF3-to-partner and partner-to-IGSF3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Lacrimal gland development grouped by IGSF3-low versus IGSF3-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF3→partner) and Y-score (partner→IGSF3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Lacrimal gland development →	+1.530	+2.597	<.001	<.001	3	20
SKIN	Aerobic respiration →	+0.066	+1.528	.004	.005	3	12
OESOPHAGUS	Cytoplasmic translation →	+0.080	+1.744	.008	.006	3	11
BLOOD_Lymphoma	Cellular respiration →	+0.068	+1.663	<.001	<.001	3	11
BLOOD_Lymphoma	Negative regulation of myoblast fusion →	+0.093	+1.211	<.001	.005	3	10
LUNG_SCLC	Negative regulation of syncytium formation by plasma membrane fusion →	+0.091	+1.526	.004	<.001	2	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,532 associations by consensus.

Lacrimal gland development by IGSF3 expression — LIVER

Explore this box plot interactively →