Across TCGA cell cohorts, IGSF23 RNA expression is significantly associated with the RNA expression of many other genes, with 3,361 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible IGSF23-associated genes across cancer lineages are PVR, CEACAM19, and GFI1B. Each is linked with IGSF23 in more than 6 cancer types. Because this analysis shows association rather than direction, both IGSF23-to-partner and partner-to-IGSF23 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF23→partner) and Y-score (partner→IGSF23) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	PVR →	+1.384	+0.447	<.001	<.001	2	7
BONE	CEACAM19 →	+1.433	+0.389	<.001	.001	3	5
BLOOD_Leukemia	GFI1B →	+2.630	+0.071	<.001	.004	3	4
LUNG_NSCLC_LUAD	RAB5IF →	+0.685	+0.347	<.001	.003	3	3
BONE	NLRC5 →	+1.410	+0.247	.004	.005	2	4
OVARY	KMT2B →	+0.863	+0.866	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,361 associations by consensus.

Exploration

IGSF23 survival (RNA) · tumor vs normal (RNA) · all IGSF23 data types