IGSF11

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGSF11 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,754 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGSF11-associated proteins across cancer lineages are RCOR3, SAFB, and SP100_S18. Each is linked with IGSF11 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGSF11-to-partner and partner-to-IGSF11 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF11 versus RCOR3 in HNSC, with a Pearson correlation of 0.50.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF11→partner) and Y-score (partner→IGSF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCRCOR3 →+0.326+0.846<.001<.00134
GBMSAFB →+0.293+0.663<.001.00134
PDACSP100_S18 →-0.477-0.773<.001<.00134
GBMIRF2BP1 →+0.349+0.734<.001<.00134
PDACLIN7C →+0.282+0.749<.001<.00134
GBMUPP1 →-1.092-0.788<.001<.00134
Each partner links to its Q-omics profile. Showing the 6 strongest of 16,754 associations by consensus.

IGSF11 vs RCOR3 — HNSC

Per-sample scatter of IGSF11 vs RCOR3 in HNSC (Pearson r = 0.50).

Explore this scatter interactively →

Exploration