IGSF1

Across TCGA patient cohorts, IGSF1 RNA expression is significantly associated with the RNA expression of many other genes, with 14,345 significant associations in total. THYM shows the largest number of these associations.

The most reproducible IGSF1-associated genes across cancer lineages are SALL2, ARHGAP36, and USP51. Each is linked with IGSF1 in more than 22 cancer types. Because this analysis shows association rather than direction, both IGSF1-to-partner and partner-to-IGSF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF1 versus SALL2 in SARC, with a Pearson correlation of 0.41.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF1→partner) and Y-score (partner→IGSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SARC	SALL2 →	+1.210	+1.172	<.001	<.001	3	23
THCA	ARHGAP36 →	+5.164	+3.356	<.001	<.001	3	22
THYM	USP51 →	+1.138	+1.084	<.001	<.001	3	22
UCS	EPC2 →	+0.661	+1.745	<.001	.001	3	22
SARC	VANGL2 →	+1.832	+0.734	<.001	.003	3	21
UCEC	C1GALT1C1L →	+0.935	+0.674	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 14,345 associations by consensus.

IGSF1 vs SALL2 — SARC

Explore this scatter interactively →