IGSF1

Across TCGA patient cohorts, IGSF1 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,612 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGSF1-associated proteins across cancer lineages are PIK3CA, CCNL1_S374, and CNDP2. Each is linked with IGSF1 in more than 3 cancer types. Because this analysis shows association rather than direction, both IGSF1-to-partner and partner-to-IGSF1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGSF1 versus PIK3CA in LSCC, with a Pearson correlation of 0.39.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGSF1→partner) and Y-score (partner→IGSF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PIK3CA →	+0.312	+1.074	<.001	<.001	3	4
UCEC	CCNL1_S374 →	+0.462	+0.882	<.001	<.001	3	4
HNSC	CNDP2 →	-0.350	-0.841	<.001	<.001	3	4
UCEC	SDF2 →	+0.486	+0.857	<.001	.001	3	4
UCEC	KIF13B →	-0.319	-0.631	<.001	<.001	3	4
LSCC	UNG →	+0.586	+1.119	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,612 associations by consensus.

IGSF1 vs PIK3CA — LSCC

Explore this scatter interactively →