IGLVVII-41-1

Across TCGA pan-cancer cohorts, IGLVVII-41-1 RNA is linked to patient survival in 10 of 34 cancer types, making it the most broadly survival-associated IGLVVII-41-1 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher IGLVVII-41-1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGLVVII-41-1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and SKCM show a favorable association.

DLBC, KIRC, and STAD are the cancer types where IGLVVII-41-1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	DFS	Tertile	All	0.358	0.848	<.001	63	view →
KIRC	DFS	Tertile	All	0.144	0.634	.001	48	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	39	view →
HNSC	OS	Tertile	II,III,IV	0.885	0.732	.029	27	view →
COAD	OS	Tertile	IV	0.089	0.658	.012	18	view →
LUSC	OS	Tertile	III,IV	0.171	0.795	<.001	18	view →
THCA	DFS	Tertile	IV	0.146	0.795	.004	18	view →
UCEC	DFS	Tertile	IV	0.206	0.704	.033	18	view →
SKCM	DFS	Tertile	All	0.816	0.611	.027	6	view →
CESC	DFS	Tertile	All	1.000	0.727	.038	6	view →

Pink = unfavorable, green = favorable. Showing the 10 strongest of 10 lineages.

IGLVVII-41-1–DLBC (DFS)

Open the DLBC breakdown →