Q-omics provides the consensus-scored IGLVVII-41-1 profile across patient tissues and cancer cell-line models. IGLVVII-41-1 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in DLBC. Among the 18 cancer types available for tumor–normal comparison, IGLVVII-41-1 is differentially expressed in 2, with the highest sampling consensus in READ. Additionally, IGLVVII-41-1 RNA expression shows 5,694 significant gene co-expression associations, with the highest sampling consensus in KIRP. Together, these results highlight DLBC, READ, and KIRP as cancer lineages where IGLVVII-41-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for IGLVVII-41-1 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes IGLVVII-41-1 survival associations across molecular data types. IGLVVII-41-1 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible IGLVVII-41-1 RNA expression–survival associations across cancer types. High IGLVVII-41-1 expression shows unfavorable associations in DLBC, KIRC, STAD, LUSC and UCEC, but favorable associations in HNSC. The DLBC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify DLBC as the clearest survival context for IGLVVII-41-1 RNA expression.
This table summarizes IGLVVII-41-1 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 2. The strongest signals are observed in READ for RNA.
This table ranks reproducible tumor–normal expression differences for IGLVVII-41-1. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. IGLVVII-41-1 shows lower tumor expression in READ and higher tumor expression in LUAD. The READ box plot shows higher IGLVVII-41-1 RNA expression in normal versus tumor tissue (log2 FC = −0.222, t-test p = .021).
This table shows molecular features associated with IGLVVII-41-1 in patient tissues and cancer cell lines. In patient samples, IGLVVII-41-1 shows the broadest associations at the RNA and protein expression levels, with KIRP recurring as the lineage with the largest associated feature set.
