IGLVVI-22-1

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLVVI-22-1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,061 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGLVVI-22-1-associated GO terms across cancer lineages are Positive regulation of protein localization to cell surface, Regulation of protein secretion, and Response to calcium ion. Each is linked with IGLVVI-22-1 in more than 2 cancer types. Because this analysis shows association rather than direction, both IGLVVI-22-1-to-partner and partner-to-IGLVVI-22-1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein localization to cell surface grouped by IGLVVI-22-1-low versus IGLVVI-22-1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLVVI-22-1→partner) and Y-score (partner→IGLVVI-22-1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
STADPositive regulation of protein localization to cell surface →+0.112+0.049<.001.00433
STADRegulation of protein secretion →+0.121+0.069<.001.00233
STADResponse to calcium ion →+0.086+0.060<.001.00433
STADGalactose metabolic process →+0.107+0.062<.001.00633
STADCellular response to amyloid-beta →+0.106+0.038<.001.00332
STADDouble-strand break repair via classical nonhomologous end joining →+0.084+0.036<.001.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,061 associations by consensus.

Positive regulation of protein localization to cell surface by IGLVVI-22-1 expression — STAD

Box plot of Positive regulation of protein localization to cell surface in IGLVVI-22-1-low vs IGLVVI-22-1-high samples in STAD.

Explore this box plot interactively →

Exploration