IGLVV-58

Across TCGA patient cohorts, IGLVV-58 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,117 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGLVV-58-associated GO terms across cancer lineages are Positive regulation of DNA metabolic process, Regulation of protein ubiquitination, and Obsolete cellular response to extracellular stimulus. Each is linked with IGLVV-58 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGLVV-58-to-partner and partner-to-IGLVV-58 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA metabolic process grouped by IGLVV-58-low versus IGLVV-58-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLVV-58→partner) and Y-score (partner→IGLVV-58) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Positive regulation of DNA metabolic process →	+0.069	+0.128	<.001	<.001	3	10
STAD	Regulation of protein ubiquitination →	+0.076	+0.146	<.001	<.001	3	9
STAD	Obsolete cellular response to extracellular stimulus →	+0.066	+0.120	<.001	<.001	3	9
STAD	Nuclear envelope organization →	+0.085	+0.114	<.001	<.001	3	9
STAD	Protein-RNA complex organization →	+0.077	+0.125	<.001	<.001	3	9
STAD	RNA modification →	+0.069	+0.133	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,117 associations by consensus.

Positive regulation of DNA metabolic process by IGLVV-58 expression — STAD

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