IGLVIVOR22-2

Across TCGA patient cohorts, IGLVIVOR22-2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,883 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible IGLVIVOR22-2-associated GO terms across cancer lineages are N-terminal protein amino acid acetylation, Protein acylation, and N-terminal peptidyl-methionine acetylation. Each is linked with IGLVIVOR22-2 in more than 28 cancer types. Because this analysis shows association rather than direction, both IGLVIVOR22-2-to-partner and partner-to-IGLVIVOR22-2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, N-terminal protein amino acid acetylation grouped by IGLVIVOR22-2-low versus IGLVIVOR22-2-high in UVM.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLVIVOR22-2→partner) and Y-score (partner→IGLVIVOR22-2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UVM	N-terminal protein amino acid acetylation →	+0.068	+0.170	<.001	<.001	3	29
ESCA	Protein acylation →	+0.067	+0.299	<.001	<.001	3	29
DLBC	N-terminal peptidyl-methionine acetylation →	+0.078	+0.304	<.001	<.001	3	28
ESCA	Obsolete histone H3-K4 methylation →	+0.092	+0.338	<.001	<.001	3	28
ESCA	Nuclear-transcribed mRNA catabolic process →	+0.077	+0.327	<.001	<.001	3	28
DLBC	Negative regulation of gene expression, epigenetic →	+0.065	+0.345	<.001	<.001	3	28

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,883 associations by consensus.

N-terminal protein amino acid acetylation by IGLVIVOR22-2 expression — UVM

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