IGLVIVOR22-2

Across TCGA pan-cancer cohorts, IGLVIVOR22-2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated IGLVIVOR22-2 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher IGLVIVOR22-2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGLVIVOR22-2 expression acts as an unfavorable survival marker, although some lineages such as READ and LUAD show a favorable association.

ACC, UVM, and READ are the cancer types where IGLVIVOR22-2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	III,IV	0.231	0.642	<.001	111	view →
UVM	OS	Tertile	III,IV	0.480	0.901	<.001	95	view →
READ	OS	Tertile	All	1.000	0.569	.006	33	view →
KICH	DFS	Quartile	All	0.421	0.951	<.001	31	view →
TGCT	DFS	Quartile	II,III,IV	0.586	1.000	.004	30	view →
LUAD	OS	Tertile	All	0.822	0.646	.002	25	view →
COAD	OS	Quartile	III,IV	0.218	0.606	.011	22	view →
PRAD	DFS	Quartile	All	0.814	0.911	.002	18	view →
KIRP	DFS	Quartile	All	0.432	0.672	.009	12	view →
CHOL	DFS	Tertile	All	1.000	0.258	.012	9	view →
LIHC	OS	Tertile	III,IV	0.344	0.563	.031	6	view →
LGG	DFS	Tertile	All	0.787	0.864	.021	5	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

IGLVIVOR22-2–ACC (OS)

Open the ACC breakdown →