IGLVIV-66-1

Q-omics provides the consensus-scored IGLVIV-66-1 profile across patient tissues and cancer cell-line models. IGLVIV-66-1 expression is associated with patient survival in 13 of 34 cancer types, with the highest sampling consensus in LUSC. Additionally, IGLVIV-66-1 RNA expression shows 5,961 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight LUSC, and STAD as cancer lineages where IGLVIV-66-1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes IGLVIV-66-1 survival associations across molecular data types. IGLVIV-66-1 RNA expression shows survival associations in the most cancer types (13). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGLVIV-66-1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	13	LUSC (45)	view →

This table ranks reproducible IGLVIV-66-1 RNA expression–survival associations across cancer types. High IGLVIV-66-1 expression shows unfavorable associations in LUSC, BLCA, OV, COAD and GBM, but favorable associations in SKCM. The LUSC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .015). Together, the overview and detailed table identify LUSC as the clearest survival context for IGLVIV-66-1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUSC	OS	Tertile	III,IV	0.341	0.601	.015	45	view →
BLCA	DFS	Tertile	IV	0.109	0.481	<.001	36	view →
OV	OS	Tertile	IV	0.022	0.760	<.001	36	view →
SKCM	OS	Tertile	All	1.000	0.848	.010	27	view →
COAD	OS	Tertile	III,IV	0.191	0.701	.038	18	view →
GBM	OS	Tertile	All	0.103	0.415	.003	18	view →

Pink = unfavorable, green = favorable. all 13 lineages →

IGLVIV-66-1-LUSC (OS)

Explore this curve interactively →