IGLVIV-65

Across TCGA pan-cancer cohorts, IGLVIV-65 RNA is linked to patient survival in 7 of 34 cancer types, making it the most broadly survival-associated IGLVIV-65 data layer.

The strongest signal is observed in esophageal carcinoma (ESCA), where higher IGLVIV-65 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated IGLVIV-65 expression acts as an unfavorable survival marker.

ESCA, LUSC, and SARC are the cancer types where IGLVIV-65 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	72	view →
LUSC	OS	Tertile	II,III,IV	0.133	0.732	<.001	54	view →
SARC	OS	Tertile	All	0.022	0.861	<.001	36	view →
PRAD	DFS	Tertile	All	0.140	0.777	<.001	30	view →
GBM	DFS	Tertile	All	0.074	0.261	.001	18	view →
LUAD	OS	Tertile	II,III,IV	0.141	0.677	.002	18	view →
THCA	DFS	Tertile	All	0.710	0.908	.016	12	view →

Pink = unfavorable, green = favorable. Showing the 7 strongest of 7 lineages.

IGLVIV-65–ESCA (OS)

Open the ESCA breakdown →