Q-omics provides the consensus-scored IGLVIV-65 profile across patient tissues and cancer cell-line models. IGLVIV-65 expression is associated with patient survival in 7 of 34 cancer types, with the highest sampling consensus in ESCA. Additionally, IGLVIV-65 RNA expression shows 5,211 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight ESCA, and STAD as cancer lineages where IGLVIV-65 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

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Survival associations

This table summarizes IGLVIV-65 survival associations across molecular data types. IGLVIV-65 RNA expression shows survival associations in the most cancer types (7). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

IGLVIV-65 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	7	ESCA (72)	view →

This table ranks reproducible IGLVIV-65 RNA expression–survival associations across cancer types. High IGLVIV-65 expression shows unfavorable associations in ESCA, LUSC, SARC, PRAD, LUAD and GBM. The ESCA Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .003). Together, the overview and detailed table identify ESCA as the clearest survival context for IGLVIV-65 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ESCA	OS	Tertile	All	0.198	0.872	.003	72	view →
LUSC	OS	Tertile	II,III,IV	0.133	0.732	<.001	54	view →
SARC	OS	Tertile	All	0.022	0.861	<.001	36	view →
PRAD	DFS	Tertile	All	0.140	0.777	<.001	30	view →
LUAD	OS	Tertile	II,III,IV	0.141	0.677	.002	18	view →
GBM	DFS	Tertile	All	0.074	0.261	.001	18	view →

Pink = unfavorable, green = favorable. all 7 lineages →

IGLVIV-65-ESCA (OS)

Kaplan–Meier survival curve for IGLVIV-65 RNA expression in ESCA: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGLVIV-65 in patient tissues and cancer cell lines. In patient samples, IGLVIV-65 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
Function (RNA)	5,211	STAD (5087)	view →
RNA	2,954	STAD (1577)	view →