IGLVIV-64

associated omics data
immunoglobulin lambda variable (IV)-64 (pseudogene)Genealiases: IGLV(IV)-64 · IGLVIV64 · V4-8P

Q-omics provides the consensus-scored IGLVIV-64 profile across patient tissues and cancer cell-line models. IGLVIV-64 expression is associated with patient survival in 6 of 34 cancer types, with the highest sampling consensus in CESC. Additionally, IGLVIV-64 RNA expression shows 5,147 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight CESC, and STAD as cancer lineages where IGLVIV-64 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Survival associations

This table summarizes IGLVIV-64 survival associations across molecular data types. IGLVIV-64 RNA expression shows survival associations in the most cancer types (6). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
IGLVIV-64 data typeSurvival analysisLineage consensusLineage of highest sampling consensus
RNAKaplan–Meier6BRCA (36)view →
This table ranks reproducible IGLVIV-64 RNA expression–survival associations across cancer types. High IGLVIV-64 expression shows unfavorable associations in CESC, BRCA, HNSC, KIRC and DLBC, but favorable associations in ESCA. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify CESC as the clearest survival context for IGLVIV-64 RNA expression.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CESCOSTertileIV0.1080.619<.00136view →
BRCADFSTertileIV0.1750.730.00536view →
HNSCDFSTertileIII,IV0.2060.505.02636view →
KIRCDFSTertileIV0.2190.620.00118view →
DLBCOSTertileII,III,IV0.1180.802.02518view →
ESCAOSTertileAll0.8450.440.0476view →
Pink = unfavorable, green = favorable. all 6 lineages →

IGLVIV-64-CESC (OS)

Kaplan–Meier survival curve for IGLVIV-64 RNA expression in CESC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with IGLVIV-64 in patient tissues and cancer cell lines. In patient samples, IGLVIV-64 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
Associated data typeStrength (# associated data)Lineage of highest associated data
RNA
Function (RNA)5,147STAD (4034)view →
RNA3,269HNSC (1028)view →