IGLVIV-59

Across TCGA pan-cancer cohorts, IGLVIV-59 RNA differs between tumor and matched normal tissue in 1 of 18 cancer types tested, making tumor–normal expression one of IGLVIV-59’s most consistent transcriptional readouts.

The strongest signal is observed in kidney chromophobe (KICH), where IGLVIV-59 RNA is repressed in tumor relative to normal tissue. In most cancer types IGLVIV-59 is over-expressed in tumor, although a few such as KICH show the opposite, repressed pattern.

KICH are the cancer types where IGLVIV-59 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGLVIV-59 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KICH	Male	All	−0.167	.006	3	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 1 strongest of 1 lineages.

IGLVIV-59–KICH

Open the KICH breakdown →