IGLVI-63

Across TCGA patient cohorts, IGLVI-63 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,782 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible IGLVI-63-associated GO terms across cancer lineages are B cell mediated immunity, T-helper 17 type immune response, and Antigen receptor-mediated signaling pathway. Each is linked with IGLVI-63 in more than 22 cancer types. Because this analysis shows association rather than direction, both IGLVI-63-to-partner and partner-to-IGLVI-63 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, B cell mediated immunity grouped by IGLVI-63-low versus IGLVI-63-high in THCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLVI-63→partner) and Y-score (partner→IGLVI-63) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
THCA	B cell mediated immunity →	+0.090	+0.280	<.001	<.001	3	23
STAD	T-helper 17 type immune response →	+0.052	+0.254	<.001	<.001	3	23
STAD	Antigen receptor-mediated signaling pathway →	+0.059	+0.186	<.001	<.001	3	22
STAD	B cell receptor signaling pathway →	+0.074	+0.201	<.001	<.001	3	22
STAD	Immunoglobulin production →	+0.070	+0.261	<.001	<.001	3	22
STAD	Regulation of Fc-gamma receptor signaling pathway involved in phagocytosis →	+0.089	+0.217	<.001	<.001	3	21

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,782 associations by consensus.

B cell mediated immunity by IGLVI-63 expression — THCA

Explore this box plot interactively →