IGLVI-20

Across TCGA pan-cancer cohorts, IGLVI-20 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of IGLVI-20’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where IGLVI-20 RNA is repressed in tumor relative to normal tissue. In most cancer types IGLVI-20 is over-expressed in tumor, although a few such as COAD and STAD show the opposite, repressed pattern.

COAD, LUAD, and STAD are the cancer types where IGLVI-20 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in IGLVI-20 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	All	IV	−0.824	.001	8	view →
LUAD	Female	All	+0.399	<.001	6	view →
STAD	All	All	−0.364	.005	5	view →
READ	All	III,IV	−1.310	<.001	4	view →
KIRC	All	All	+0.071	.011	4	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

IGLVI-20–COAD

Open the COAD breakdown →