Across TCGA cell cohorts, IGLV9-49 protein abundance is significantly associated with the RNA expression of many other genes, with 2,058 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible IGLV9-49-associated genes across cancer lineages are ZBTB46, MRGPRF, and KCTD21. Each is linked with IGLV9-49 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGLV9-49-to-partner and partner-to-IGLV9-49 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV9-49→partner) and Y-score (partner→IGLV9-49) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	ZBTB46 →	+2.505	+0.748	.003	.001	3	5
CNS	MRGPRF →	+2.021	+0.715	.002	.001	3	4
SOFT_TISSUE	KCTD21 →	+0.876	+1.089	.003	.002	3	4
BLOOD_Lymphoma	SMARCD2 →	-0.617	-0.645	.003	.005	2	5
STOMACH	SPECC1 →	+2.982	+0.952	.003	.001	3	4
BLOOD_Lymphoma	RCN3 →	+3.542	+0.926	.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,058 associations by consensus.

Exploration

IGLV9-49 survival (RNA) · tumor vs normal (RNA) · all IGLV9-49 data types