Across TCGA patient cohorts, IGLV5-45 protein abundance is significantly associated with the protein abundance of many other proteins, with 15,207 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible IGLV5-45-associated proteins across cancer lineages are IGHV3-15, IGKV4-1, and IGHV3-7. Each is linked with IGLV5-45 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGLV5-45-to-partner and partner-to-IGLV5-45 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV5-45→partner) and Y-score (partner→IGLV5-45) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	IGHV3-15 →	+1.242	+1.551	<.001	<.001	3	9
BRCA	IGKV4-1 →	+0.920	+1.299	<.001	<.001	3	9
OV	IGHV3-7 →	+0.904	+1.055	<.001	<.001	3	8
OV	IGLL1 →	+0.854	+1.097	<.001	<.001	3	8
OV	IGLV2-8 →	+1.607	+1.300	<.001	<.001	3	8
LUAD	IGLV3-19 →	+1.030	+1.192	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,207 associations by consensus.

Exploration

IGLV5-45 survival (RNA) · tumor vs normal (RNA) · all IGLV5-45 data types