Across TCGA patient cohorts, IGLV4-60 protein abundance is significantly associated with the RNA expression of many other genes, with 8,284 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV4-60-associated genes across cancer lineages are IGLV6-57, IGHV3-20, and IGKV3-20. Each is linked with IGLV4-60 in more than 4 cancer types. Because this analysis shows association rather than direction, both IGLV4-60-to-partner and partner-to-IGLV4-60 results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV4-60→partner) and Y-score (partner→IGLV4-60) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	IGLV6-57 →	+2.438	+0.889	<.001	.003	3	5
LUAD	IGHV3-20 →	+1.912	+0.856	<.001	.004	3	4
OV	IGKV3-20 →	+3.208	+1.053	.001	.005	3	4
OV	IGHV2-70 →	+2.166	+1.092	.004	.002	3	4
OV	IGHV1-69D →	+2.514	+1.094	.001	<.001	3	4
OV	LMOD1 →	+1.172	+1.191	.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,284 associations by consensus.

Exploration

IGLV4-60 survival (RNA) · tumor vs normal (RNA) · all IGLV4-60 data types