Across TCGA patient cohorts, IGLV3-9 mutation is significantly associated with the RNA expression of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLV3-9-associated genes across cancer lineages are BPNT2P, MIR513A1, and RN7SL551P. Each is linked with IGLV3-9 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV3-9-to-partner and partner-to-IGLV3-9 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-9→partner) and Y-score (partner→IGLV3-9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	BPNT2P →	+0.066	+3.661	<.001	.009	3	2
COAD	MIR513A1 →	+0.447	+5.283	<.001	.006	3	1
COAD	RN7SL551P →	+0.381	+5.790	.005	.003	3	1
SKCM	MIR6076 →	+0.428	+3.730	<.001	.008	3	1
LUSC	RNA5SP426 →	+0.318	+7.924	<.001	.008	3	1
LUSC	MIR489 →	+0.420	+7.924	<.001	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

Exploration

IGLV3-9 survival (RNA) · tumor vs normal (RNA) · all IGLV3-9 data types