IGLV3-7

Across TCGA patient cohorts, IGLV3-7 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,457 significant associations in total. STAD shows the largest number of these associations.

The most reproducible IGLV3-7-associated GO terms across cancer lineages are Natural killer cell mediated immunity, Natural killer cell activation, and Nucleobase-containing compound transport. Each is linked with IGLV3-7 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGLV3-7-to-partner and partner-to-IGLV3-7 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Natural killer cell mediated immunity grouped by IGLV3-7-low versus IGLV3-7-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-7→partner) and Y-score (partner→IGLV3-7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Natural killer cell mediated immunity →	+0.069	+0.121	<.001	<.001	3	9
STAD	Natural killer cell activation →	+0.075	+0.158	<.001	<.001	3	8
STAD	Nucleobase-containing compound transport →	+0.111	+0.151	<.001	<.001	3	7
THYM	Meiotic spindle organization →	+0.105	+0.503	<.001	<.001	3	7
STAD	Electron transport chain →	+0.117	+0.150	<.001	<.001	3	7
STAD	Cell cycle G1/S phase transition →	+0.096	+0.153	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,457 associations by consensus.

Natural killer cell mediated immunity by IGLV3-7 expression — STAD

Explore this box plot interactively →