IGLV3-7

Across TCGA pan-cancer cohorts, IGLV3-7 RNA is linked to patient survival in 9 of 34 cancer types, making it the most broadly survival-associated IGLV3-7 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher IGLV3-7 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated IGLV3-7 expression acts as an unfavorable survival marker, although some lineages such as THYM and SKCM show a favorable association.

LUAD, STAD, and UCEC are the cancer types where IGLV3-7 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Tertile	IV	0.342	0.893	<.001	39	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	27	view →
UCEC	OS	Tertile	All	0.846	0.933	.015	18	view →
LIHC	OS	Tertile	III,IV	0.094	0.615	<.001	18	view →
KIRC	DFS	Tertile	All	0.415	0.661	.015	12	view →
THYM	OS	Median	All	1.000	0.771	.008	11	view →
GBM	DFS	Tertile	All	0.060	0.242	.016	9	view →
SARC	DFS	Tertile	All	0.236	0.600	.021	9	view →
SKCM	DFS	Tertile	III,IV	0.530	0.243	.037	3	view →

Pink = unfavorable, green = favorable. Showing the 9 strongest of 9 lineages.

IGLV3-7–LUAD (DFS)

Open the LUAD breakdown →