IGLV3-6

Across TCGA patient cohorts, IGLV3-6 RNA expression is significantly associated with the protein abundance of many other proteins, with 5,226 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV3-6-associated proteins across cancer lineages are IL16, IRF4, and UBE2J1. Each is linked with IGLV3-6 in more than 5 cancer types. Because this analysis shows association rather than direction, both IGLV3-6-to-partner and partner-to-IGLV3-6 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, IGLV3-6 versus IL16 in UCEC, with a Pearson correlation of 0.40.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-6→partner) and Y-score (partner→IGLV3-6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	IL16 →	+0.509	+0.343	<.001	.002	3	6
LSCC	IRF4 →	+0.793	+0.765	<.001	<.001	3	6
LUAD	UBE2J1 →	+0.490	+0.610	<.001	<.001	3	6
BRCA	CD38 →	+0.816	+0.365	<.001	<.001	3	6
LSCC	CSDE1_S514 →	+0.856	+0.739	<.001	<.001	3	6
UCEC	MZB1 →	+1.118	+0.318	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,226 associations by consensus.

IGLV3-6 vs IL16 — UCEC

Explore this scatter interactively →