IGLV3-27

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV3-27 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLV3-27-associated genes across cancer lineages are Ku80 and c-Met_pY1235. Each is linked with IGLV3-27 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV3-27-to-partner and partner-to-IGLV3-27 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-27→partner) and Y-score (partner→IGLV3-27) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECKu80 →+0.375+2.820.009.03632
UCECc-Met_pY1235 →+0.133+2.817.003.03621
Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

Exploration