Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGLV3-19 mutation is significantly associated with the RNA expression of many other genes, with 61 significant associations in total. SKCM shows the largest number of these associations.
The most reproducible IGLV3-19-associated genes across cancer lineages are KRTAP1-4, SC4MOP, and USP12PY. Each is linked with IGLV3-19 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV3-19-to-partner and partner-to-IGLV3-19 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGLV3-19→partner) and Y-score (partner→IGLV3-19) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.