IGLV3-12

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV3-12 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,600 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV3-12-associated proteins across cancer lineages are MZB1, CD38, and MYO1G. Each is linked with IGLV3-12 in more than 8 cancer types. Because this analysis shows association rather than direction, both IGLV3-12-to-partner and partner-to-IGLV3-12 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV3-12→partner) and Y-score (partner→IGLV3-12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVMZB1 →+1.309+0.873<.001<.00139
LSCCCD38 →+0.806+1.380<.001<.00138
GBMMYO1G →+0.566+0.225<.001.00437
LSCCACAP1 →+0.536+1.379<.001<.00137
LSCCSEC11C →+0.927+1.353<.001<.00137
BRCASEPTIN1 →+0.787+1.465<.001<.00137
Each partner links to its Q-omics profile. Showing the 6 strongest of 10,600 associations by consensus.

Exploration