Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGLV2-14 mutation is significantly associated with the RNA expression of many other genes, with 81 significant associations in total. UCEC shows the largest number of these associations.
The most reproducible IGLV2-14-associated genes across cancer lineages are TRAJ36, LIMS3, and NDE1P2. Each is linked with IGLV2-14 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV2-14-to-partner and partner-to-IGLV2-14 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGLV2-14→partner) and Y-score (partner→IGLV2-14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.