Across TCGA patient cohorts, IGLV1-50 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,087 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible IGLV1-50-associated GO terms across cancer lineages are Regulation of leukocyte apoptotic process, B cell mediated immunity, and Antibacterial humoral response. Each is linked with IGLV1-50 in more than 27 cancer types. Because this analysis shows association rather than direction, both IGLV1-50-to-partner and partner-to-IGLV1-50 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-50→partner) and Y-score (partner→IGLV1-50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CHOL	Regulation of leukocyte apoptotic process →	+0.065	+1.755	.001	.002	3	28
CHOL	B cell mediated immunity →	+0.098	+1.922	<.001	<.001	3	27
THCA	Antibacterial humoral response →	+0.152	+1.412	<.001	<.001	3	27
STAD	Immunoglobulin production →	+0.088	+1.549	<.001	<.001	3	27
THCA	Humoral immune response mediated by circulating immunoglobulin →	+0.139	+1.243	<.001	<.001	3	27
ESCA	Positive regulation of leukocyte cell-cell adhesion →	+0.050	+0.609	<.001	<.001	3	27

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,087 associations by consensus.

Exploration

IGLV1-50 survival (RNA) · tumor vs normal (RNA) · all IGLV1-50 data types