Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts
Across TCGA patient cohorts, IGLV1-50 mutation is significantly associated with the RNA expression of many other genes, with 102 significant associations in total. COAD shows the largest number of these associations.
The most reproducible IGLV1-50-associated genes across cancer lineages are LINC02499, RNY1P8, and MIR6515. Each is linked with IGLV1-50 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV1-50-to-partner and partner-to-IGLV1-50 results are reported.
Each partner links to its own Q-omics profile.
mutation associated genes by consensus
Ranked by combined sampling and lineage consensus. X-score (IGLV1-50→partner) and Y-score (partner→IGLV1-50) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.