IGLV1-47

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV1-47 mutation is significantly associated with the RNA expression of many other genes, with 33 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLV1-47-associated genes across cancer lineages are IGHVII-67-1, OR4K16P, and RNU6-839P. Each is linked with IGLV1-47 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV1-47-to-partner and partner-to-IGLV1-47 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-47→partner) and Y-score (partner→IGLV1-47) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAIGHVII-67-1 →+0.591+7.640<.001.00931
BLCAOR4K16P →+0.039+7.640<.001.00931
BLCARNU6-839P →+0.313+7.640<.001.00931
BLCARN7SKP6 →+0.119+7.640<.001.00931
BLCAMIR521-1 →+0.367+7.640<.001.00931
BLCADHFRP5 →+0.069+7.640<.001.00931
Each partner links to its Q-omics profile. Showing the 6 strongest of 33 associations by consensus.

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