Across TCGA patient cohorts, IGLV1-44 RNA expression is significantly associated with the protein abundance of many other proteins, with 16,359 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible IGLV1-44-associated proteins across cancer lineages are CD48, DOCK2, and HCLS1. Each is linked with IGLV1-44 in more than 9 cancer types. Because this analysis shows association rather than direction, both IGLV1-44-to-partner and partner-to-IGLV1-44 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-44→partner) and Y-score (partner→IGLV1-44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	CD48 →	+0.852	+2.662	<.001	<.001	3	10
LSCC	DOCK2 →	+0.582	+2.149	<.001	<.001	3	10
GBM	HCLS1 →	+0.616	+1.409	<.001	<.001	3	10
OV	IL16 →	+0.610	+3.912	<.001	<.001	3	10
BRCA	ISG20 →	+0.813	+2.915	<.001	<.001	3	10
OV	MZB1 →	+1.350	+3.766	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,359 associations by consensus.

Exploration

IGLV1-44 survival (RNA) · tumor vs normal (RNA) · all IGLV1-44 data types