Across TCGA patient cohorts, IGLV1-44 mutation is significantly associated with the RNA expression of many other genes, with 43 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible IGLV1-44-associated genes across cancer lineages are RNU6-92P, MIR367, and RNA5SP205. Each is linked with IGLV1-44 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV1-44-to-partner and partner-to-IGLV1-44 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-44→partner) and Y-score (partner→IGLV1-44) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNU6-92P →	+0.196	+4.069	<.001	.008	3	1
UCEC	MIR367 →	+0.581	+2.783	<.001	.008	3	1
UCEC	RNA5SP205 →	+0.398	+3.852	<.001	.002	3	1
UCEC	RNU6-13P →	+0.355	+3.063	.002	.004	3	1
UCEC	SNORD116-3 →	+0.357	+3.299	.001	.006	3	1
UCEC	MIR191 →	+0.477	+3.343	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 43 associations by consensus.

Exploration

IGLV1-44 survival (RNA) · tumor vs normal (RNA) · all IGLV1-44 data types