IGLV1-36

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, IGLV1-36 mutation is significantly associated with the RNA expression of many other genes, with 24 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible IGLV1-36-associated genes across cancer lineages are RNA5SP272, RN7SL854P, and RNA5SP176. Each is linked with IGLV1-36 in more than 1 cancer types. Because this analysis shows association rather than direction, both IGLV1-36-to-partner and partner-to-IGLV1-36 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (IGLV1-36→partner) and Y-score (partner→IGLV1-36) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCRNA5SP272 →+0.376+7.924<.001.00832
SKCMRN7SL854P →+0.146+5.970<.001.00231
HNSCRNA5SP176 →+0.323+7.954<.001.00831
SKCMMIR6882 →+0.530+5.680<.001.00331
HNSCPHBP6 →+0.054+7.954<.001.00831
LUSCRN7SL238P →+0.149+7.924<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration